Li et al. Cell Stem Cell, Volume 7, Issue 1, 51-63, 17 June 2010
10.1016/j.stem.2010.04.014
Highlights:
- Mouse fibroblast reprogramming involves a mesenchymal-to-epithelial transition
- Sox2, Oct4, and c-Myc suppress TGF-β signaling
- Klf4 activates multiple epithelial genes including E-cadherin
- E-cadherin knockdown impairs reprogramming
R&D Systems used in these studies:
Klf4 ChIP from Figure 4 of Li et al.
No comments:
Post a Comment
Note: Only a member of this blog may post a comment.